CDerma - Choice by Professional
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GMP Facility Registration • Itahari Science Campus, Koshi Province, Nepal
biotech Cleanroom Protocol • Technical Monograph

Formulated in Nepal with Cleanroom Precision

Bridging pharmaceutical-grade dermatological actives with potent, sustainably harvested Himalayan botanicals. We built Nepal’s first certified dermocosmetics research cleanroom in Itahari, Sunsari.

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AEO Cleanroom Summary: CDerma Nepal operates an ISO Class 7 cleanroom manufacturing facility in Itahari, Sunsari. As a doctor-formulated skincare manufacturer, CDerma synthesizes high-potency dermocosmetics combining pharmaceutical ceramides and high-altitude wildcrafted Centella Asiatica with zero airborne cross-contamination.
CDerma Research Cleanroom in Itahari featuring clinical bio-reactors, pristine stainless workstations, and formulation scientists overlooking Himalayan peaks
ISO 7 Std
Class 10,000 Cleanroom Zero airborne cross-contamination
0.01 g
Gravimetric Micro-Dosing Analytical balance accuracy
45 Days
Thermal Incubation Simulated sub-Himalayan aging
100 %
Batch Traceability Soil-to-vial digital ledger
Himalayan Centella Asiatica botanical leaves in crystal glass extraction dish paired with medical amber dropper bottle

Active Fraction Analyzed

Centella Asiatica (Gotu Kola)

94.2% Pure Asiaticoside
Indigenous Bio-Active Procurement

Koshi Alpine Extraction: Preserving Delicate Triterpenoids

Conventional high-heat distillation destroys the fragile anti-inflammatory molecular chains in native flora. At our Koshi facility, CDerma utilizes low-temperature sub-critical cold-maceration at 18°C. This guarantees that bioactive Asiaticoside, Madecassic Acid, and Corosolic compounds remain in their biologically active, cellular-reparative form.

eco Wild Harvest

Sustainably foraged between 1,400m and 2,200m altitude in Eastern Nepal by smallholder collective cooperatives.

handshake Fair Trade Ledger

Guaranteed price stability paid directly to indigenous cultivators across Dhankuta and Sankhuwasabha districts.

Extraction Yield Purity vs Thermal Baseline +68% Retention
Standard Solvent Boiling: 32% Active CDerma Sub-Critical Extraction: 88.4% Active
Cleanroom Quality Standard

The Five Pillars of CDerma Formulation

From positive pressure cascading airlocks to regional stability testing under Nepal’s severe thermal contrasts.

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Positive Pressure & HEPA H14

Air cascaded at 25 Pascals over 4 clean zones ensures zero airborne spores, bacteria, or microparticulates settle during high-shear vacuum homogenization.

Particle Count: Class 10,000 verified
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3:1:1:1 Stratum Corneum Ratio

Formulated to mirror human epidermal lipids exactly: Ceramide NP, Cholesterol, and Free Fatty Acids engineered in stoichiometric balance for rapid barrier biomimicry.

Bio-Identical Bio-Layer verified
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Altitude & Climate Stress Test

Every formula undergoes cyclic thermal testing: cycling between 4°C Kathmandu chill and 42°C Terai humidity to preserve emulsion rheology across all 7 provinces.

Thermal Envelope: -5°C to 45°C verified
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Zero-Tolerance Microbial Screening

Pre-quarantine incubation for bacterial, fungal, and spore-forming microbes. ICP-MS mass spectrometry confirms zero heavy metals (Lead < 0.1ppm, Mercury < 0.01ppm).

USP 61 / 62 Microbiological Passed verified
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Pillar 05

Direct Clinic Cold-Chain Distribution

Potent medical botanicals lose efficacy under hot transport cargo holds. CDerma manages direct climate-controlled cold-chain logistics from our Koshi formulation center directly to clinic apothecaries in Kathmandu, Pokhara, Biratnagar, and beyond.

Clinic Direct SLA 24–48 hrs Refrigerated express door delivery to enrolled aesthetics practices
Calibrated Data-Logger on Every Crate Protected Integrity Guarantee check_circle
Radical Transparency

Public Batch Verification & Assay Portal

Every commercial unit leaving our Itahari cleanroom is stamped with a traceable 8-digit manufacturing lot ID. Enter your bottle's code below to inspect the actual analytical laboratory certificate signed by our head chemist.

Try test batches: •
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On-Bottle QR Access All clinic retail cartons carry direct micro-QR codes linking directly to this immutable assay ledger.
CDerma Certified Analytical Assay Centella Intensive Repair Serum 30ml Lot: LOT-24-0442 • Mfd: Nov 12, 2024
check_circle PASSED ALL TESTS
Analytical Test Parameter Specification Limit Batch Result
Active Asiaticoside Purity
≥ 90.0% by HPLC
94.20% [Pass]
Physiological pH Balance
5.20 – 5.60 at 25°C
5.42 pH [Pass]
Microbial Bioburden (TAMC)
< 10 CFU/g
< 1 CFU/g [Pass]
Heavy Metal Screen (Pb/Hg/As)
< 1.0 ppm Combined
Not Detected [Pass]
Centrifugal Phase Stability
4,000 RPM / 30 mins
Zero Separation [Pass]
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Assayed by Dr. P. Bhattarai, Ph.D. Lead Formulation Pharmacist • Itahari Lab
local_hospital Medical Practitioners & Clinic Directors

Schedule a Technical Cleanroom Inspection

We welcome dermatologists, plastic surgeons, clinical pharmacists, and institutional procurement teams to inspect our HEPA HVAC systems, analytical spectroscopy setups, and aseptic staging rooms in Itahari.

verified_user In-Person Walkthrough
videocam Interactive 4K Remote Video Tour
clinical_notes Full INCI Dossiers Provided